Re: Kartagener syndrome with focal segmental glomerulosclerosis.

348 Iranian Journal of Kidney Diseases | Volume 8 | Number 4 | July 2014 stress, although there is no bacterial infection. In these situations, after the elevation of procalcitonin values, a rapid decline is observed in the follow-up measurements. 3 On the other hand, procalcitonin can have false negative or lower values in early course and localized site of an infection. 3 In this context, repeated measurements of procalcitonin could have been performed. Therefore, it would have been better if the authors had mentioned these conditions as limitations. Lastly, procalcitonin is affected by a variety of infectious agents. Microbiological assessment is crucial while evaluating the procalcitonin levels. In comparisons of Gram negative agents with Gram positives, procalcitonin levels have been found to be higher in Gram negatives. 4 Therefore, it would have been more accurate, if the authors had evaluated procalcitonin levels according to infectious agents in greater detail in this study. In conclusion, further studies are needed to determine the association between procalcitonin and VUR. We are of the opinion that procalcitonin should be evaluated with other independent variables and markers (eg, bacterial agents, C-reactive protein, and erythrocyte sedimentation rate) to provide the required information about the inflammatory status of the patient.